P450 mixed-function oxidase reaction

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Generalized electron transport system for the P450 mixed-function oxidases

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Common Cytochrome P450 Catalyzed Reactions
Aromatic hydroxylation
Aliphatic hydroxylation  
N-Dealkylation  
O-Dealkylation  
Deamination
N-Oxidation
Sulphoxidation

 

 

 

 

 

 

 

 

 

 

 

 

 

NIH-shift mechanism for hydroxylations involving an epoxide intermediate

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Transformation of Aldrin to Dieldrin.

chemical equation for the transformation of aldrin to dieldrin

 

 

 

 

 

 

 

 

 

 

 

 

 

Transformation of naphthalene to naphthol

chemical equations for the

 

 

 

 

 

 

 

 

 

 

 

 

 

Benzopyrene trans-epoxide

chemical structure diagram of the trans-epoxide of benzopyrene

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Benzene metabolic products

chemical equation for the metabolism of napthol via an epoxide to 1-napthol and 2-napthol

 

Last modified 25 February 2010

© RA Paselk 2001