Humboldt State University ® Department of Chemistry

Richard A. Paselk

Chemistry 438 - Spring 2013

ETS & Oxidative Phosphorylation Review

Redox Energy Calculation:

• Calculate the efficiency of energy capture in the oxidation of NADH by the electron transport system. KEY

Consider the relative reduction pattern of the ETS in the presence of NADH (highly reduced) oxygen (highly oxidized) and low [ADP].

What would a plot of reduction vs. ETS components (e.g. NADH, FADH₂, CoQH₂, cyt C, etc.) look like? KEY

Calculations of P/O ratios

Calculate the P/O ratio (ATPs produced for each oxygen atom consumed) for the aerobic catabolism of glucose in mammalian fast twitch muscle. Show all work in a table such as we have used in class. KEY

Do this calculation again for glucose in insect flight muscle. KEY

• Why should this difference exist? (That is, why should evolution favor this lower value of energy for insect flicht muscle?)

Fatty Acid Oxidation

Calculate the P/O ratio for the aerobic catabolism of stearate (C=18). Show all work in a table such as we have used in class. KEY

 

Schedule

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©R A Paselk

Last modified 3 April 2013