Glycogen Metabolism
- How is glycogen metabolism controlled in muscle?
- Cascade amplification
- Hormone mediated G-protein activation
- cAMP "second messenger" Protein Kinase activation
- Protein kinase enzyme phosphorylation/activation
- allosteric effectors to match local needs
- What is the energy advantage of storing glucose as glycogen
in muscle? (get 3 ATP/Glucose vs. 2 ATP/Glucose)
- How does this advantage come about?
(glucose is released as G-1-P, so HK step not needed)
- What is the % quantitative advantage? (50%)
- Is the storage of glucose as glycogen in muscle an energetic
advantage to the organism overall? (muscle glycogen is NOT available for use by the rest of the body, so is not advantageous in terms of starvation etc. Of course in exercise it can spare other body energy sources)
- If not, why do it? (more than one answer!).
©R A Paselk
Last modified 3 April 2013
