Humboldt State University ® Department of Chemistry

Richard A. Paselk

Chemistry 438 - Spring 2013

Carbohydrate Metabolism Review

Give a pathway for the breakdown of glycerol to acetyCoA, naming enzyme types and energy steps.

Answer:

  • glycerol glycerol-P (Kinase) -1 ATP
  • glycerol-P DHAP (DH) 1 NADH
  • DHAP Ga-3-P
  • Ga-3P 1,3-bisPGA (DH) 1 NADH
  • 1,3-bisPGA 3-PGA (Kinase) 1 ATP
  • 3-PGA 2-PGA PEP
  • PEP Pyruvate (Kinase) 1 ATP
  • Pyruvate acetylCoA (DH Complex) 1 NADH

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

What are the main entrance/exit points of carbohydrate metabolism?

Answer:

  • glycogen enters/exits at G-6-P
  • glycerol enters/exits at DHAP (see above)
  • Pentose P Shunt (also R-5-P)
    • exits at G-6-P
    • enters/exits (for transformation rxns) at F-6-P and Ga-3-P
  • Kreb's TCA Cycle intermediates
    • catabolism
      • enter with acetylCoA adding to oxalacetate
    • anapleurosis
      • enters at PEP via oxalacetate/malate
      • exits at Pyruvate via oxalacetate/malate
  • Fructose (human liver) enters/exits at DHAP via F-1-P
  • Galactose enters/exits at G-6-P

 

Schedule

 

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©R A Paselk

Last modified 3 April 2013