Humboldt State University ® Department of Chemistry

Richard A. Paselk

Chemistry 438 - Spring 2011

BIOCHEMISTRY REVIEW

Week 13

Fat Metabolism, cont.

Exercise: Calculate the P/O ratio for the aerobic catabolism of stearate (C=18). Show all work in a table such as we have used in class. return to Review
 Reaction Energy Product Factor Multiplier ATP Equiv.
ATP Equivalents
(@3 ATP/NADH)

 O's
FACoA Syn. AMP -2 1 -2 -2
Flavin DH FADH2 1.5 8 12 16 8
NAD+ DH NADH 2.5 8 20 24  8

8 AcCoA's to Kreb's TCA Cycle
NADH 2.5 x 3 9 67.5 81  27
GTP 1 9 9 9  0
FADH2 1.5 9 13.5 18  9

Total=

120 146  52
P/O = ATP/O =
120/52 = 2.31 146/52 = 2.81  

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©R A Paselk

Last modified 20 April 2011