Humboldt State University ® Department of Chemistry

Richard A. Paselk

Chem 438

Introductory Biochemistry

Spring 2007

Lecture Notes: 5 March

© R. Paselk 2006


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Membrane Assembly/Protein Targeting

Assembly occurs on scaffolding of previous membrane

Membrane lipids are synthesized in/on membrane (Eukaryotes synthesis on cytosolic face of ER, transport by budding and Phospholipid exchange protein. Signal hypothesis for targeting of many membrane and exported proteins:

Proteins are transported in coated vesicles: membranous sacs encased in polyhedral frameworks of clathrin. (Figure 22.29) [overhead 11-42, 21-17, V&V

Introduction to Vitamins and Cofactors


Let's start with a brief overview of the names, structures and physiological functions of the common vitamins as shown on the overhead: Niacin, Riboflavin [B2], Thiamine, Pantothenic acid, Biotin, Pyridoxal [B6], Folic acid, Lipoic acid, Cobalamin [B12], L-Ascorbic acid [C], and the lipid soluble vitamins A, D, E, and K). Fun facts:

Pathway Diagrams

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Last modified 5 March 2007