Chem 432 Lecture Notes, Spring 2009

These are the notes I use to present my lectures. They are here for the convenience of my students. They are unedited and thus liable to error. The expansions and corrections I put in during my lectures are not included. If you find errors in these notes, please inform me ASAP via e-mail: rap1 @ axe.humboldt.edu

• Lecture 1; January 21: Introduction; Mitochondrial Cross-membrane Exchange Systems.
• Lecture 2; January 23: Malate-Aspartate Shuttle; Chloroplasts and Photosynthesis.
• Lecture 3; January 26: Photosynthesis - The Light Reactions; The Calvin Cycle.
• Lecture 4; January 28: The Calvin Cycle - RuBisCo; Fatty Acid Biosynthesis.
• Lecture 5; January 30: Fatty Acid Biosynthesis, cont. - the Pyruvate-Malate Cycle; Fatty Acid Elongation and Desaturation (Mixed Function Oxidases). Lecture 5 slide
• Lecture 6; February 2: Regulation of Fatty Acid Metabolism; The Glyoxalate Cycle; The Biosynthesis of Triacylglycerols and Phospholipids. Lecture 6 slide
• Lecture 7; February 4: Chlesterol Biosynthesis. Lecture 7 slide
• Lecture 8; February 6: Nitrogen Metabolism; Amino Acid Transamination and Deamination. Lecture 8 slide
• Lecture 9; February 9: Nitrogen Metabolism, cont. - Deamination, cont.; Urea Cycle. Lecture 9 slide
• Lecture 10; February 11: Nitrogen Metabolism, cont. - Tissue Specificity in Amino Acid Metabolism;Alanine Cycle; Amino Acid Carbon Skeleton Catabolim. Lecture 10 slide
• Lecture 11; February 13: Skeleton Catabolism, cont.; The One-Carbon Pool. Lecture 11 slide
• Lecture 12; February 16: The One-Carbon Pool, cont.; Nitrogen Fixation. Lecture 12 slide
• Lecture 13; February 18: Nitrogen Fixation, cont.; Protein Degredation; Nucleotide Metabolism - Purine Biosynthesis. Lecture 13 slide
• Lecture 14; February 23: Pyrimidine Biosynthesis; Nucleotide Degredation; Metabolic Integration. Lecture 14 slide
• Lecture 15; February 25: Metabolic Integration, cont. - Exercise. Lecture 15 slide
• Lecture 16; February 27: DNA, RNA & Nucleic Acid Structure; DNA Structure and Folding. Lecture 16 slide
• Lecture 17; March 2: DNA Structure and Folding, cont.; DNA Supercoiling.
• Lecture 18; March 9: DNA Structure and Folding, cont.; Topoisomerases, c_ot curves; Chromosomes.
• Lecture 19; March 11: DNA Replication - Polymerases.
• Discussion 1; March 13: Hypoglycemia - Read case discussion before class and be ready to contribute.
• Lecture 20; March 23: Eukaryotic DNA Replication - Polymerases.
• Lecture 21; March 25: Eukaryotic DNA Replication - Polymerases, cont.; Chromosome Replication; DNA Repair.
• Lecture 22; March 27: RNA.
• Discussion 2 ; March 30: HIV/AIDS
• Lecture 23; April 1: Transcription;E. coli RNA Polymerase.
• Discussion; April 3: HIV/AIDS cont.
• Lecture 24; April 6: Transcription, cont, Eukaryotic RNA Polymerases; Translation - The Genetic Code; Aminoacyl tRNA Synthetases; Wobble and Code Degeneracy.
• Lecture 25; April 8: Translation - Ribosomes; Ribosome Structure; Polypeptide Synthesis.

Schedule

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Syllabus

Last modified 9 April 2009