Glycogen Metabolism
- Know reactions for incorporating Glu-6-P into glycogen.
- What is the function of UDPG?
- Why is PPi released in Transferase reaction?
- Synthase reaction
- Glycogen synthesis requires a primer.
- Why do organisms have synthase and phosphorylase? (why not just phosphorylase?)
- Phosphorylase reaction.
- How much energy is required to incorporate one Glucose into glycogen (in ATP units)?
- How many ATP's result from glycolysis starting with
- glycogen?
- glucose?
- Why difference?
- How is glycogen debranched?
- What activities are required?
- How is glycogen metabolism controlled in muscle? KEY
- note "futile cycles" in phosphorylation/dephosphorylation of proteins - what effect do they have on control? response?)
- What is the energy advantage of storing glucose as glycogen in muscle?
- How does this advantage come about?
- What is the % quantitative advantage?
- Is the storage of glucose as glycogen in muscle an energetic advantage to teh organism overall?
- If not, why do it? (more than one answer!).
©R A Paselk
Last modified 9 December 2008