Humboldt State University ® Department of Chemistry

Richard A. Paselk

Know the major branch points and entry points for sugars in carbohydrate metabolism (see metabolism handouts):
Know the "bypass" reactions of gluconeogenesis.
How is glycolysis/gluconeogenesis linked to Kreb's Cycle?
What is a futile cycle?
- Is a futile cycle always futile or can it be useful?
Know how glycolysis/gluconeogenesis controlled.
- Note the hierarchy of control.
- In what senses does PFK function as the main and most important control enzyme in glycolysis.
- Know what substances act as effectors for PFK and how they work.
- Why is AMP used as the physiological regulator of PFK activity in advanced organisms (modern bacteria - eukaryotes)
- Know how PFK activity indirectly affects the activities of the other control enzymes of glycolysis/gluconeogenesis.
- Be able to discuss in detail the regulation of carbohydrate metabolism and, in particular, the regulation of PFK.

Schedule

C431 Home

C438 Lecture Notes

©R A Paselk

Last modified 13 November 2008