Chem 431 Lecture Notes, Fall 2008
These are the notes
I use to present my lectures. They are here for the convenience
of my students. They are unedited and thus liable to error. The
expansions and corrections I put in during my lectures are not
included. If you find errors in these notes, please inform me
ASAP via e-mail: rap1 @
axe.humboldt.edu
- Lecture 1; 25 August: Introduction;
What is Biochemistry?
-
Lecture 2; 27 August: Characteristics of Life, cont.; Cells and Organelles.
- Lecture 3; 29 August: Cells and Organelles; Elements of of Life.
- Lecture 4; 3 September: The Molecules of Life.
- Lecture 5; 3 September: Origin of Life; Early Evolution of Life.
- Lecture 6; 8 September: Water. Lecture 6 slide
- Lecture 7; 10 September: Water, cont. - Ionization etc.
- Lecture 8; 12 September: Buffers; Amino Acids 1.
- Lecture 9; 15 September: Amino Acids 2; Peptides and Amino Acid Chemistry.
- Lecture 10; 17 September: Peptide Bond Geometry; 3-D Structure of Proteins 1.
- Lecture 11; 19 September: 3-D Structure of Proteins 2.
- Lecture 12; 22 September: 3-D Structure of Proteins 3. Lecture 12 slide
- Lecture 13; 24 September: 3-D Structure of Proteins 4, Tertiary & Quaternary Structures.
- Lecture 14; 26 September: 3-D Structure of Proteins 5, Symmetry in Quaternary Structures; Protein Folding.
- Lecture 15; 29 September: Protein Folding, cont.; Myoglobin and Hemoglobin as Example Proteins.
- Lecture 16; 1 October: Myoglobin and Hemoglobin as Example Proteins, cont.; Allosterism and Regulation; Introduction to Enzymes.
- Lecture 17; 3 October: Enzyme Specificity; Introduction to Kinetics; Enzyme Kinetics.
- Lecture 18; 6 October: Enzyme Kinetics, cont.; Linear Plots; Enzyme Inhibition.
- Lecture 19; 8 October: Enzyme Inhibition, cont.; Multi-Substrate Enzyme Kinetics; Temperture Effects.
- Lecture 20; 10 October: Enzyme pH Effects; Allosteric Enzymes; Introduction to Catalysis.
- Lecture 21; 13 October: Mechanisms of Catalysis. Chymotrypsin as an Example Enzyme.
- Lecture 22; 15 October: Lysozyme as an Example Enzyme; Introduction to Carbohydrates.
- Lecture 23; 17 October: Carbohydrates, cont.
- Lecture 24; 20 October: Carbohydrates 3; Lipids.
- Lecture 25; 22 October: Lipids, cont.
- Lecture 26; 24 October: Biological Membranes.
- Lecture 27; 27 October: Membrane Assembly/Protein Targeting; Introduction to Cofactors and Vitamins.
- Lecture 28; 29 October: Cofactors and Vitamins, cont.; Introduction to Metabolism.
- Lecture 29; 31 October: Introduction to Metabolism, cont.: Pathway Characteristics, Stages of Catabolism, Organic Reaction Types, High-energy Compounds; Introduction to Thermodynamics in Metabolism.
- Lecture 30; 3 November: Thermodynamics in Metabolism; Carbohydrate Digestion; Introduction to Glycolysis.
- Lecture 31; 5 November: Glycolysis, cont.
- Lecture 32; 7 November: Glycolysis 3.
- Lecture 33; 10 November: Glycolysis 4.
- Lecture 34; 12 November: Glycolysis 5; Lactate DH; Gluconeogenesis.
- Lecture 35; 14 November: Gluconeogenesis, cont.; Pyruvate Metabolism.
- Lecture 36; 17 November: Kreb's Tricarboxylic Acid Cycle.
- Lecture 37; 19 November: Kreb's Tricarboxylic Acid Cycle, cont.
- Lecture 38; 21 November: Kreb's Tricarboxylic Acid Cycle 3; Glycogen Metabolism.
- Lecture 39; 1 December: Glycogen Metabolism Control; Pentose Phosphate Shunt.
- Lecture 40; 3 December: Pentose Phosphate Shunt - Sugar Interconversion Reactions; Lipid Metabolism.
- Lecture 41; 5 December: Beta-Oxidation of Fatty acids.
- Lecture 42; 8 December: Ketone Body Metabolism.
- Lecture 43; 10 December: Mitochondrial Electron Transport.
- Lecture 44; 12 December: The Electron Transport System and Oxidative Phosphorylation.
Last modified 12 December 2008
Pathway Diagrams